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Grant funders / South Dakota / Sioux Falls

Grant Funders in Sioux Falls, SD

Bespoke Grants indexes 49 grant-making foundations headquartered in Sioux Falls, South Dakota — together $309.6M in indexed annual giving. Their giving most often supports health care, higher education, faith-based (christian) and arts & culture. Local funders are one of the best starting points for a Sioux Falls nonprofit, because many prioritize organizations in their own community.

49
Foundations in Sioux Falls
$309.6M
Indexed annual giving
40
Listed below
SD
State

Foundations headquartered in Sioux Falls

Ranked by giving in available IRS summaries. Filings may cover different years; these totals are not a current-year funding pool. Each links to a public overview and up to three sample grants. Full grant history and research tools require All access at $19/month.

#FoundationAnnual givingLatest grant
1Esther and Harold Mertz Foundation$57.4M2024
2Sanford Group Return$49.6M2024
3Sanford Health Foundation$36.1M2024
4Sioux Falls Area Community$18.4M2024
5Sioux Falls Development$16.0M2024
6Avera Health$15.9M2023
7Edith Sanford Breast Cancer Foundation$15.5M2018
8Denny Sanford Foundation$10.3M2024
9Sfs Foundation$8.4M2025
10Sioux Empire United Way Inc$7.7M2024
11Aditi Foundation$6.6M2024
12The Evangelical Lutheran Good Samaritan$6.1M2024
13Sanford Health Foundation North$5.7M2024
14Butterfly House & Aquarium Inc$4.0M2022
15Margot and Tom Pritzker Foundation$3.5M2024
16Lifescape Foundation$3.2M2024
17David H Billion Foundation$3.0M2024
18Branches Foundation$2.9M2023
19Ch Robinson Worldwide Foundation$2.9M2024
20Mccrossan Foundation Inc$2.8M2025
21Via-bradley College of Engineering Found$2.7M2024
22Houston Family Foundation$2.6M2024
23Feeding South Dakota$2.3M2025
24Seeds of Change Foundation$2.0M2024
25The Luke Society Inc$1.5M2017
26South Dakota Association of Healthcare$1.5M2024
27Veterans of Foreign Wars of the Us$1.5M2023
28Children's Home Foundation$1.4M2025
29Raft Charitable Foundation$1.4M2023
30Milo Stip Charitable Remainder$1.4M2025
31Blythe Brenden-mann Foundation$1.4M2024
32Friends of South Dakota Public Broadcasting$1.3M2025
33Sanford Health Foundation West$1.1M2024
34Make-a-wish Foundation of South Dakota$985K2023
35Avera Mckennan$949K2023
36Comfort Family Foundation$913K2025
37First Lutheran Church Foundation$905K2024
38The Robert and Rita Elmen Foundation$787K2024
39Vasilius Family Foundation$786K2024
40The Evangelical Lutheran Good Samaritan$755K2020

Running a nonprofit in Sioux Falls?

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What Sioux Falls funders support

The causes most commonly funded by foundations based in Sioux Falls:

Beyond Sioux Falls

Local funders are a starting point, not the whole picture. Most Sioux Falls nonprofits are also eligible for statewide and national foundations — browse all grant funders in South Dakota, or let Bespoke Grants match your nonprofit to funders at every level. One lifetime free search includes up to three sourced matches; further searches and the full workflow are $19/month. No credit card is needed for the preview.

About this page. Lists foundations whose IRS Form 990 filings give a Sioux Falls, SD address, drawn from Bespoke Grants' index of 225,000+ U.S. foundations and 13M+ grants. Foundations based elsewhere may also fund Sioux Falls nonprofits; the one lifetime free funder search accounts for both.