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Grant funders / Minnesota / Mayo Clinic

Mayo Clinic

Rochester, Minnesota  ·  EIN 416011702  ·  Private foundation

Based in Rochester, Minnesota, Mayo Clinic has awarded $3.58B across 1,828 grants in our index of public IRS filings, with giving recorded as recently as 2024. Its largest grant on record went to Mayo Clinic Jacksonville. This profile covers its focus areas, top grant recipients, year-by-year giving, and how a nonprofit should approach it.

$517.7M
Annual giving (FY2020)
$16.53B
Total assets
1,828
Grants tracked
2024
Most recent grant

What Mayo Clinic funds

Mayo Clinic's giving carries a documented focus on education, health care, higher education.

EducationHealth CareHigher Education

Grant history

The largest grants Bespoke Grants has on record for Mayo Clinic, by amount:

RecipientLocationGrantYear
Mayo Clinic Jacksonville
SUPPORT CHARITABLE PROGRAMS
Jacksonville, FL$479.8M2017
Mayo Clinic Jacksonville
SUPPORT CHARITABLE PROGRAMS
Jacksonville, FL$346.1M2023
Mayo Foundation for Medical Education and Research
SUPPORT CHARITABLE PROGRAMS
Rochester, MN$266.0M2023
Mayo Clinic Arizona
SUPPORT CHARITABLE PROGRAMS
Scottsdale, AZ$205.2M2019
Mayo Clinic Arizona
SUPPORT CHARITABLE PROGRAMS
Scottsdale, AZ$163.1M2020
Mayo Clinic Jacksonville
SUPPORT CHARITABLE PROGRAMS
Jacksonville, FL$152.2M2019
Mayo Clinic Arizona
SUPPORT CHARITABLE PROGRAMS
Scottsdale, AZ$121.0M2022
Mayo Clinic Jacksonville
SUPPORT CHARITABLE PROGRAMS
Jacksonville, FL$120.3M2024
Mchs--southwest Minnesota Region
SUPPORT CHARITABLE PROGRAMS
Mankato, MN$118.4M2024
Mayo Clinic Jacksonville
SUPPORT CHARITABLE PROGRAMS
Jacksonville, FL$113.6M2020
Mayo Clinic Arizona
SUPPORT CHARITABLE PROGRAMS
Scottsdale, AZ$113.4M2023
Mayo Clinic Jacksonville
SUPPORT CHARITABLE PROGRAMS
Jacksonville, FL$102.5M2022
Mayo Clinic Arizona
SUPPORT CHARITABLE PROGRAMS
Scottsdale, AZ$97.5M2024
Mchs--southwest Wisconsin Region Inc
SUPPORT CHARITABLE PROGRAMS
La Crosse, WI$96.0M2024
Okefenokee Health Inc (fka Mchs in Waycross Inc)
SUPPORT CHARITABLE PROGRAMS
Waycross, GA$90.4M2017

Mayo Clinic giving by year

Total grants Bespoke Grants has indexed for each filing year:

2017$680.9M
2018$188.8M
2019$448.5M
2020$493.9M
2022$292.0M
2023$903.2M
2024$572.1M

How to apply for funding from Mayo Clinic

Mayo Clinic's public IRS filing does not spell out a formal application process. Foundations of this size often give primarily to organizations they already know, so a concise letter of inquiry or a warm introduction is usually the best first contact — not a full proposal. You can review the foundation directly at mayoclinic.org.

Is Mayo Clinic the right funder for your nonprofit?

This page shows what Mayo Clinic has funded. Bespoke Grants tells you whether it fits your mission — and finds every other foundation that does. Free, no credit card.

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Frequently asked questions about Mayo Clinic

Does Mayo Clinic accept grant applications?
Mayo Clinic's public filing does not specify an application process. A brief letter of inquiry or a warm introduction is usually the best first step with a private foundation of this size.
What does Mayo Clinic fund?
Mayo Clinic's grants focus on education. Recent recipients include Mayo Clinic Jacksonville, Mayo Clinic Jacksonville, Mayo Foundation for Medical Education and Research. Its full grant history is listed above.
How much does Mayo Clinic give in grants?
Mayo Clinic reported $517.7M in grants in its most recent IRS filing (FY2020). Across all years in our data it has awarded $3.58B over 1,828 grants.
Where is Mayo Clinic located?
Mayo Clinic is based in Rochester, Minnesota. Its IRS employer identification number (EIN) is 416011702.
How can I find foundations similar to Mayo Clinic?
Bespoke Grants matches your nonprofit against 225,000+ foundations like Mayo Clinic, ranking each by how well it fits your mission, location, and budget — with the reasoning shown. It is free to search.

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Foundations similar to Mayo Clinic

Other Minnesota grantmakers with overlapping priorities:

About this profile. This page is built from Mayo Clinic's public IRS Form 990-PF and 990 filings, indexed by Bespoke Grants alongside 13M+ grants from 225,000+ U.S. foundations. Grant figures reflect filings available to date; IRS data publishes on a 1–2 year lag. Bespoke Grants is not affiliated with Mayo Clinic. Always confirm current giving priorities and application procedures with the foundation directly before applying.