Grant funders / South Carolina / Mental Health
Mental Health Grant Funders in South Carolina
39 foundations with a documented mental health focus have made grants to South Carolina nonprofits in recent years, together directing $19.9M to organizations across the state. Below are the most active — every funder links to a full giving profile, and Bespoke Grants will match all 39 against your nonprofit's specific mission, for free.
39
Mental health funders
$19.9M
Given to South Carolina nonprofits
194
Grants on record
2025
Most recent giving
Most active mental health funders in South Carolina
| # | Funder | Based in | Total South Carolina giving | Grants | Latest |
|---|---|---|---|---|---|
| 1 | The Duke Endowment | North Carolina | $13.6M | 48 | 2024 |
| 2 | The David and June Trone Family Foundation | Maryland | $1.7M | 2 | 2023 |
| 3 | Mary Black Foundation Inc | South Carolina | $949K | 12 | 2024 |
| 4 | South Carolina Association for | South Carolina | $929K | 16 | 2023 |
| 5 | The Byerly Foundation | South Carolina | $276K | 3 | 2024 |
| 6 | Community Foundation of the Lowcountry | South Carolina | $254K | 7 | 2023 |
| 7 | Spartanburg Regional Healthcare System | South Carolina | $174K | 17 | 2023 |
| 8 | National Community Reinvestment | District of Columbia | $153K | 3 | 2019 |
| 9 | Hollingsworth Funds Inc | South Carolina | $150K | 3 | 2023 |
| 10 | Bon Secours Mercy Health Inc | Ohio | $147K | 2 | 2017 |
| 11 | Pdmh Board Foundation | South Carolina | $118K | 4 | 2024 |
| 12 | Cardinal Health Foundation | Ohio | $100K | 2 | 2025 |
| 13 | United Way of Horry County Inc | South Carolina | $90K | 6 | 2020 |
| 14 | Carolinas Center for Medical Excellence Found | Delaware | $80K | 2 | 2024 |
This list is ranked by size. Yours should be ranked by fit.
The funders above are the biggest mental health funders in South Carolina — not necessarily the right ones for you. Bespoke Grants ranks all 39 against your nonprofit's actual mission, service area, and budget, and shows you why each one matches. Free, no credit card.
Rank these funders for my nonprofit →Mental Health funders in other states
Other causes funded in South Carolina
How this list is built. Bespoke Grants indexes 13M+ grants from public IRS Form 990 filings. This page shows foundations whose giving carries a documented mental health focus and that have funded South Carolina nonprofits. Giving figures reflect each funder's total recent grants to South Carolina recipients. IRS data publishes on a 1–2 year lag; figures are current through the most recent available filings.